The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.
应用类型
WB, IHC
免疫原
该Anti-Mouse Galectin-7的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Mouse Galectin-7的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Mouse Galectin-7的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Mouse Galectin-7的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
