- 中文名称
Anti-Human BMP-2
- 英文名字
- Anti-Human BMP-2
- 供应商
- ReliaTech
- 产品货号
- 102-P03A
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Human BMP-2 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor β (TGFβ) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation. However, they have since been shown to be involved in embryogenesis and morphogenesis of various tissues and organs. BMPs have also been shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. Similarly to other TGFβ family proteins, BMPs are highly conserved across animal species. At the amino acid sequence level, mature human, mouse and rat BMP2 are 100% identical. BMP2 is synthesized as a large precursor protein that is cleaved at the dibasic cleavage site (RXXR) to release the carboxyterminal domain. Biologically active BMP 2 is a disulfidelinked homodimer of the carboxyterminal 114 amino acid residues that contains the characteristic seven conserved cysteine residues involved in the formation of the cysteine knot and the single interchain disulfide bond. Cellular responses to BMP2 have been shown to be mediated by the formation of heterooligomeric complexes of type I and type II serine/threonine kinase receptors. One BMP type II and two BMP type I receptors have been identified. In contrast to the TGFβ type I receptor, which does not bind the ligand in the absence of the TGFβ receptor type II, both BMP receptor type Is can bind BMP2 with highaffinity in the absence of BMP receptor type II.
- 应用类型
- ELISA, WB
- 免疫原
- 该Anti-Human BMP-2的详细信息查看ReliaTech提供的产品说明书。
- 来源宿主
- Rabbit
- 反应性
- 该Anti-Human BMP-2的详细信息查看ReliaTech提供的产品说明书。
- 保存建议
- 该Anti-Human BMP-2的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
- 其他
- ReliaTech全称为受体配体技术有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，总部位于德国不伦瑞克，是一家后基因组生物技术公司。ReliaTech主要专注于受体和配体的发现与研究。此外，ReliaTech也开发应用于血管与淋巴管生成研究的相关高品质试剂。目前ReliaTech提供近2800款产品，产品线主要包括重组蛋白(细胞因子、生长因子、可溶性受体)、抗体、ELISA试剂盒等。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
-
