The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. IL-1 R1 is a type I transmembrane glycoprotein that functions as the ligand binding subunit in the IL-1 receptor complex. It associates with a signaling component, IL-1 R3 (IL-1 receptor accessory protein) to form a functional receptor complex for IL-1 alpha and IL-1 beta.
应用类型
WB
免疫原
该Anti-Human IL-1 R1的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human IL-1 R1的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human IL-1 R1的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human IL-1 R1的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
