Cathepsin E is an intracellular aspartic protease of the pepsin family. Unlike Cathepsin D, another member of the same family and a lysosomal protease with relatively ubiquitous distribution, Cathepsin E is not a lysosomal enzyme and has a limited cell and tissue distribution. However, both Cathepsin D and E play an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. Both enzymes are efficient in cleaving Swedish mutant of amyloid precursor protein (APP) at the β site but show almost no reactivity with wildtype APP. Human Cathepsin E is synthesized as a precursor protein, consisting of a signal peptide (aa 1-17), a propeptide (aa 18-53), and a mature chain (aa 54-396).
应用类型
WB
免疫原
该Anti-Human Cathepsin E的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human Cathepsin E的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human Cathepsin E的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human Cathepsin E的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
