CCL14 is a chemokine that promotes chemotaxis of T cells, monocytes, and eosinophils. It occurs in two isoforms resulting from differential mRNA splicing. Following cleavage of a 19 amino acid signal peptide, mature CCL14a (aa 20-93) is a 74 amino acid peptide that is also known as HCC1 (Hemofiltrate CC Chemokine1). It is a weak CCR1 agonist, however, an 8 amino acid Nterminal truncation (aa 28 93) allows potent signaling through CCR1 and CCR5. CCL14b, also called HCC3, is a 90 amino acid peptide (aa 20-109) resulting from the insertion of 16 amino acids between residues 7 and 8 of CCL14a.
应用类型
WB, N
免疫原
该Anti-Human CCL-14的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human CCL-14的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human CCL-14的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human CCL-14的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
