- 中文名称
Anti-Human BMP-1
- 英文名字
- Anti-Human BMP-1
- 供应商
- ReliaTech
- 产品货号
- 101-M231
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- Bone morphogenetic protein 1 (BMP1), also known as procollagen Cproteinase (PCP), is a zinc protease of the astacin family. BMP1/ PCP plays a key role in formation of extracellular matrix (ECM) by converting precursor proteins into their mature and functional forms. The precursor proteins identified as substrates for BMP1/ PCP include collagens, biglycan, laminin 5, dentin matrix protein1, and lysyl oxidase. There are six alternatively spliced forms known to be derived from the BMP 1 gene, and isoform 1 consisting of residues 1 to 730 was expressed. The secreted and purified protein does not contain the signal peptide (amino acid residues 122) and pro domain (residues 23-120), but contain protease (residues 121-321), CUB I (residues 322-434), CUB II (residues 435-546), EGFlike (residues 547-588) and CUB III (residues 591-703) domains. The pro domain is apparently cleaved by a furinlike proprotein convertase. The purified BMP1/ PCP is an active protease and its peptidase activity can be determined as described above. The purified BMP1/ PCP is predicted to possess procollagen C proteinase activity because it contains the minimal domain structure required.
- 应用类型
- WB, IHC
- 免疫原
- 该Anti-Human BMP-1的详细信息查看ReliaTech提供的产品说明书。
- 来源宿主
- 该Anti-Human BMP-1的详细信息查看ReliaTech提供的产品说明书。
- 反应性
- 该Anti-Human BMP-1的详细信息查看ReliaTech提供的产品说明书。
- 保存建议
- 该Anti-Human BMP-1的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- 其他
- ReliaTech全称为受体配体技术有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，总部位于德国不伦瑞克，是一家后基因组生物技术公司。ReliaTech主要专注于受体和配体的发现与研究。此外，ReliaTech也开发应用于血管与淋巴管生成研究的相关高品质试剂。目前ReliaTech提供近2800款产品，产品线主要包括重组蛋白(细胞因子、生长因子、可溶性受体)、抗体、ELISA试剂盒等。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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