Cleavage of amyloid precursor protein (APP) into 40 or 42 amino acid amyloid β (aβ) peptides is a result of the action of two proteases β- and γ-secretase. The beta-site APP cleaving enzyme, or BACE-1, is a transmembrane aspartic protease that is localized in the Golgi and endosomes. Low levels of BACE-1 mRNA are found in most adult tissues with a higher level of expression in pancreas.
应用类型
WB, IHC (P)
免疫原
该Anti-Human BACE-1的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human BACE-1的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human BACE-1的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human BACE-1的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
