- 中文名称
Anti-Human B7-H2
- 英文名字
- Anti-Human B7-H2
- 供应商
- ReliaTech
- 产品货号
- 101-M225
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Cathepsins of the papain family can be divided into two functional groups. One group comprises ubiquitously expressed, intracellular housekeeping proteases responsible for the general lysosomal protein breakdown. The cathepsins L, B, H, and probably O (1, 2) belong to this group. The other group is characterized by a tissue restricted expression pattern and by the assignment of specific functions correlated with their tissue distribution. For example, cathepsin S, the first known tissue-specific cysteine protease is primarily expressed in lymphatic tissues (3,4) and is responsible for the specific degradation of the invariant chain of MHC class II complexes in antigen-presenting cells (5, 6). Cathepsin K, which is predominantly expressed in osteoclasts, is a major protease in bone resorption (7-9). All presently known thiol-dependent cathepsins share common protein structures with a signal sequence of 16–18 amino acids, followed by a propeptide of 62–100 residues and then a catalytically active mature region of about 220–230 amino acids (1). The propart is involved in the folding of the precursor protein, in the temporary inhibition of the protease in its precursor form, and in transport of the proenzyme to the endosomal/lysosomal compartment using mannose 6-phosphateN-glycosylation sites (10,11). Finally, the mature, catalytically active, enzyme contains the catalytic triad consisting of Cys-25, His-159, and Asn-175 (papain numbering) and is folded into a two-domain structure. In addition, thiol-dependent cathepsins have been characterized as lysosomal enzymes, since they have signal sequences and potential N-glycosylation sites and generally have pH optima in the acidic pH range.
- 应用类型
- WB, N
- 免疫原
- 该Anti-Human B7-H2的详细信息查看ReliaTech提供的产品说明书。
- 来源宿主
- 该Anti-Human B7-H2的详细信息查看ReliaTech提供的产品说明书。
- 反应性
- 该Anti-Human B7-H2的详细信息查看ReliaTech提供的产品说明书。
- 保存建议
- 该Anti-Human B7-H2的详细信息查看ReliaTech提供的产品说明书。溶解建议：Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- 其他
- ReliaTech全称为受体配体技术有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，总部位于德国不伦瑞克，是一家后基因组生物技术公司。ReliaTech主要专注于受体和配体的发现与研究。此外，ReliaTech也开发应用于血管与淋巴管生成研究的相关高品质试剂。目前ReliaTech提供近2800款产品，产品线主要包括重组蛋白(细胞因子、生长因子、可溶性受体)、抗体、ELISA试剂盒等。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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