The gene for the antigen encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
应用类型
WB, FC
免疫原
该Anti-Human ADAM-17的详细信息查看ReliaTech提供的产品说明书。
来源宿主
该Anti-Human ADAM-17的详细信息查看ReliaTech提供的产品说明书。
反应性
该Anti-Human ADAM-17的详细信息查看ReliaTech提供的产品说明书。
保存建议
该Anti-Human ADAM-17的详细信息查看ReliaTech提供的产品说明书。溶解建议:Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.