- 中文名称
Harmine (5 g)
- 英文名字
- Harmine, 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
- 供应商
- Cayman
- 产品货号
- 10010324-5
- 产品报价
- ￥3584/5 g
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- Peroxisome proliferator-activated receptor .gamma. -PPAR.gamma.) is a central regulator of adipocyte differentiation and is the principle target of the thiazolidinedione -TZD) class of antidiabetic drugs. Harmine is a .beta.-carboline alkaloid that was first isolated from seeds of Peganum harmala -Syrian rue) and Banisteriopsis caapi. Recent work indicates that harmine is a unique regulator of PPAR.gamma. expression that acts by inhibiting the Wnt signalling pathway in a cell-specific manner. Administration of harmine -30 mg/kg) to obese db/db mice resulted in reduced blood glucose, free fatty acids, and triglyceride levels, delayed hyperglycemia, and improved insulin sensitivity. Harmine also attenuates inflammatory gene expression -TNF.alpha., IL-1.beta., iNOS) and macrophage accumulation in adipose tissue.
- 产品描述
- Harmine is a .beta.-carboline alkaloid that was first isolated from seeds of Peganum harmala -Syrian rue) and Banisteriopsis caapi. Recent work indicates that harmine is a unique regulator of PPAR.gamma. expression that acts by inhibiting the Wnt signalling pathway in a cell-specific manner.{14921} Administration of harmine -30 mg/kg) to obese db/db mice resulted in reduced blood glucose, free fatty acids, and triglyceride levels, delayed hyperglycemia, and improved insulin sensitivity. Harmine also attenuates inflammatory gene expression -TNF.alpha., IL-1.beta., iNOS) and macrophage accumulation in adipose tissue.{14921}
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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