- 中文名称
PtdIns-(4)-P1结合蛋白 (25 ug)
- 英文名字
- PtdIns-(4)-P1 Binding Protein (25 ug)
- 供应商
- Cayman
- 产品货号
- 10009241-25
- 产品报价
- ￥1288/25 ug
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Pleckstrin homology -PH) domains all contain a seven-standard .beta.-sandwich that allows binding to various species of phosphatidyl inositol -PtdIns) phosphates. Most PH domains bind to phosphatidylinositol phosphates -PIPs) with weak affinity and low specificity, however, a small subclass does bind specifically and with high-affinity for certain PIPs. PtdIns--4)-P1 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns--4)-P1. PIPs represent a small percentage of total membrane phospholipids however, they play a critical role in the generation and transmission of cellular signals. PtdIns--4)-P1 can phosphorylated by kinases to give bi- and triphosphates such as PtdIns--4,5)-P2 and PtdIns--3,4,5)-P3. Phosphorylation of PtdIns--4)-P1 by phosphoinositide -PI)3-kinase to make PtdIns--3,4)-P2 initiates an intricate signalling cascade that has been implicated in cancer.
- 序列
- 来源宿主
- 溶解建议
- 保存建议
- -80
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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