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中文名称

N-Palmitoyl Glycine (1 mg)

英文名字
N-Hexadecanoyl-Glycine|PalGly, N-Palmitoyl Glycine, N-(1-oxohexadecyl)-glycine
供应商
Cayman
产品货号
10009020-1
产品报价
¥182/1 mg
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背景资料
The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolamide -AEA; anandamide). N-palmitoyl glycine -PalGly) contains an 18-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. Endogenously produced in rat skin and spinal cord, PalGly is present in 100-fold greater amounts in skin and 3-fold greater in brain compared to AEA. Injection of 0.43 ug PalGly in rat hindpaw inhibits heat-induced firing of nociceptive neurons in rat dorsal horn. PalGly treatment induces transient calcium influx in native dorsal root ganglion -DRG) cells and in the PTX-sensitive, DRG-like cell line F-11 -EC50 = 5.5 uM).
产品描述
an 18-carbon saturated fatty acid that is structurally similar to the phospholipid-derived N-acyl ethanolamines; inhibits heat-induced firing of nociceptive neurons in rat dorsal horn; induces transient calcium influx in native dorsal root ganglion -DRG) cells and in the PTX-sensitive, DRG-like cell line F-11 -EC50 = 5.5 uM)
产品形式
保存建议
-20
其他
Cayman Chemical
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