- 中文名称
αβ-亚甲基ATP; 5'-[氢P-[[[羟基（膦酰氧基）膦基]甲基]膦酸酯]腺苷三钠盐
- 英文名字
- αβ-methylene ATP; 5'-[hydrogen P-[[hydroxy(phosphonooxy)phosphinyl]methyl]phosphonate] adenosine, trisodium salt
- 供应商
- Cayman Chemical
- 产品货号
- 10008956-5
- 产品报价
- ￥询价/5mg
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- α,β-methylene Adenosine 5'-triphosphate (αβ-methylene ATP) is a phosphonic analog of ATP that is characterized by the replacement of the bridging oxygen atom between the α- and β-phosphate groups with methylene. It is an agonist of P2X purinoceptors P2X1 and P2X3 (EC50 = ~1 µM) and is ~1,000-fold less potent at P2X2, P2X receptors 4-7, and P2Y receptors.{27693,27688,27691,27687} Persistent activation of purinoceptors results in desensitization, resulting in an antagonist-like effect of αβ-methylene ATP.{27689} αβ-methylene ATP is used as a stable analog of ATP (Item No. 14498) to study the interaction of ATP with kinases and other proteins.{27690,27694} It weakly binds and inhibits adenylate cyclase in a calcium-dependent manner (Ki= ~0.5 mM).{27692,27695}
- 产品描述
- A phosphonic analog of ATP and agonist of P2X1 and P2X3 (EC50 = ~1 µM); ~1,000-fold less potent at P2X2, P2X receptors 4-7, and P2Y receptors; used as a stable analog of ATP to study the interaction of ATP with kinases and other proteins
- 产品形式
- A crystalline solid
- 保存建议
- 建议您在收到Cayman Chemical品牌的α,β-methylene Adenosine 5'-triphosphate (sodium salt) (5 mg)产品后置于-20度保存，产品有效期为730天.
- 其他
- Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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