中文名称

PtdIns--3,4,5)-P3 -1,2-dihexanoyl) -ammonium salt) (5 mg)

英文名字

Phosphatidylinositol-3,4,5-triphosphate C-6|DHPI-3,4,5-P3|PIP3C-16, PtdIns--3,4,5)-P3 -1,2-dihexanoyl) -ammonium salt), 1-(1,2R-dihexanoylphosphatidyl)inositol-3,4,5-triphosphate, tetraammonium salt

供应商

Cayman

产品货号

10008390-5

产品报价

￥18620/5 mg

产品说明书

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产品新闻

背景资料

The phosphatidylinositol -PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns--3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C -PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology -PH) domains. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking. PtdIns--3,4,5)-P3 -1,2-dihexanoyl) is a synthetic analog of natural PIP3 with C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol -DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog give it different physical properties from naturally-occurring PIP3, including higher solubility in aqueous media.

产品描述

A synthetic analog of natural PIP3 with C6:0 fatty acids at the sn-1 and sn-2 positions; features the same inositol and diacylglycerol stereochemistry as the natural compound; the short fatty acid chains give it higher solubility in aqueous media, as compared to naturally-occurring PIP3.

产品形式

保存建议

-20

其他

Cayman Chemical

注意

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