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中文名称

N-Lignoceroyl Taurine (50 mg)

英文名字
N-Lignoceroyl Taurine, 2-[(1-oxotetracosyl)amino]-ethanesulfonic acid
供应商
Cayman
产品货号
10007286-50
产品报价
¥31360/50 mg
产品说明书
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产品新闻
背景资料
Several different arachidonoyl amino acid conjugates, including N-arachidonoyl dopamine and N-arachidonoyl-L-serine, have been isolated and characterized from bovine brain. N-lignoceroyl taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of brain and spinal cord from wild-type and fatty acid amide hydrolase -FAAH) knockout mice. The levels of N-lignoceroyl taurine were elevated 23-26 fold in FAAH-/- mice compared to wild-type mice, indicating that FAAH utilizes N-lignoceroyl taurine as a substrate. However, in vitro experiments with purified FAAH indicate N-lignoceroyl taurine is hydrolyzed 2,000 times more slowly by FAAH compared to oleoyl ethanolamide. N-acyl taurines bearing polyunsaturated acyl chains can activate members of the transient receptor potential -TRP) family of calcium channels, including TRPV1 and TRPV4.
产品描述
One of several novel taurine-conjugated fatty acids that act as a FAAH substrate and may activate TRPV1 and TRPV4
产品形式
保存建议
-20
其他
Cayman Chemical
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