- 中文名称
Prostaglandin D2-d4 Lipid Maps MS Standard (1 mg)
- 英文名字
- PGD2-d4, Prostaglandin D2-d4 Lipid Maps MS Standard, 9
- 供应商
- Cayman
- 产品货号
- 10007272-1
- 产品报价
- ￥30576/1 mg
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- Prostaglandin D2-d4 -PGD2-d4) contains four deuterium atoms at the 3, 3 , 4, and 4 positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as .beta.-trace.2,3 In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 uM.
- 产品描述
- 产品形式
- 保存建议
- -20
- 其他
- Cayman Chemical
- 注意
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