- 中文名称
抗PINK1多克隆抗体
- 英文名字
- PINK1 Polyclonal Antibody
- 供应商
- Cayman
- 产品货号
- 10006283-500
- 产品报价
- ￥3206/500 μl
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Phosphatase and Tensin Homolog -PTEN) dephosphorylates lipids such as phosphatidylinositol 3,4,5-triphosphate -PIP3) and its defects contribute to a variety of human cancers. PTEN induced putative kinase 1 -PINK1) was first identified when studying the tumor-suppressive function of the PTEN signaling pathway and is thus believed to be involved in human cancer pathology. The mRNA of PINK1 is expressed ubiquitously among adult tissues with most abundant expression in the heart, skeletal muscle, and testis. PINK1 is located in mitochondria and its homozygous C-terminus mutation is associated with early onset of Parkinson s disease. Cayman s PINK1 polyclonal antibody recognizes primarily the full length protein at about 66 kDa in human, mouse, and rat tissues. In addition, a truncated form of the protein at about 33 kDa is also detected.
- 应用类型
- WB and IHC -formalin-fixed paraffin-embedded sections); other applications not tested
- 免疫原
- human PINK1 amino acids 484-504 -LVRALLQREASKRPSARVAAN)
- 来源宿主
- rabbit
- 反应性
- Human PINK1+|Mouse PINK1+|Rat PINK1+|
- 保存建议
- 其他
- Cayman Chemical
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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