SETD8 is a histone methyl transferase that specifically monomethylates 'Lys-20' of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression and is enriched during mitosis. SETD8 may also play a role in maintaining silet chromatin by preventing the acetylation of the H4 tail. Anti-SETD8 Antibody is ideal for research in Gene Expression, Epigenetics and Chromatin Remodeling.
应用类型
Western Blot,
免疫原
Anti-SETD8 Antibody was produced in rabbits by repeated immunizations of the full length human SETD8 protein containing a Flag-tagged N-terminus and a His-tagged C terminus.
来源宿主
Rabbit
反应性
H. sapiens (Human); Mus musculus (Mouse)
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
