Taspine is an alkaloid isolated from Radix et Rhizoma Leonticis. It shows various pharmaceutical properties: bacteriostatic, wound healing, cytotoxicity, immunosuppression, acetilcholinesterase inhibition, and inhibition of the activity of tumor angiogenesis. Used as human acid beta-glucosidase inhibitor and for the treatment of Gaucher disease.Appearance:Supplied as an off-white to pale yellow solid.Purity~90%Melting Point:>300°C (dec.)Solubility:ChloroformMethod for Determining Identity:Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric AnalysisTLC Conditions:SiO2; Dichloromethane: Methanol: Ammonium Hydroxide = 8: 2: 0.1; Visualized with UV and KMnO4; Rf=0.50Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
