UBLE1A (also known as SAE1) or SUMO1 activating enzyme subunit 1 is involved in regulating protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (1). The SAE1/SAE2 dimer functions in SUMO1 activation in a manner analogous to the single E1 ubiquitin-activating enzymes. The SAE2 inactivation may be a therapeutic strategy in MYC-driven cancers (2). UBLE1A Protein is ideal for investigators involved in Signaling Proteins, Ubiquitin Proteins, Cancer, Cell Cycle, and Neurobiology research.
序列
该【干冰】UBLE1A (SAE1) recombinant protein-GST fusion protein - 009-001-U49的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】UBLE1A (SAE1) recombinant protein-GST fusion protein - 009-001-U49的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】UBLE1A (SAE1) recombinant protein-GST fusion protein - 009-001-U49的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
