TET1 Protein or tet methylcytosine dioxygenase 1 is the original member of a family of methylcytosine dioxygenases that perform several steps required for cytosine demethylation and gene activation (1). TET proteins have potential roles in epigenetic regulation through modification of 5mC to hmC. TET1 plays a main role in modulating DNA methylation levels at CpG-rich promoters and also helps in promoting transcription of pluripotency factors as well as participating in the repression of Polycomb-targeted developmental regulators (2). TET1 Protein is ideal for investigators involved in Signaling Proteins, Methylcytosine Dioxygenase Proteins, Cancer, and Cell Cycle research.
序列
该【干冰】TET1 recombinant protein-GST fusion protein - 009-001-U13S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】TET1 recombinant protein-GST fusion protein - 009-001-U13S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】TET1 recombinant protein-GST fusion protein - 009-001-U13S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.