SMYD2 (also known as SET and MYND domain-containing protein 2) is a member of the SMYD family of protein methyltransferases. SMYD2 is also known as lysine methyltransferase protein 3C (KMT3C). SMYD2 functions to repress transcription by interacting with the Sin3A histone deacetylase complex and performs methylation of Lys36 in histone H3 (1). The exogenous expression of SMYD2 in mouse fibroblasts decreases cell growth. SMYD2 also function as a putative oncogene by methylating p53 and repressing its tumor suppressive function (2). SMYD2 Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.
序列
该【干冰】SMYD2 recombinant protein-GST fusion protein - 009-001-T43S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】SMYD2 recombinant protein-GST fusion protein - 009-001-T43S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】SMYD2 recombinant protein-GST fusion protein - 009-001-T43S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.