PTK7 or pseudo protein tyrosine kinase 7 is a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. PTK7 lacks detectable catalytic tyrosine kinase activity but is involved in the WNT signaling pathway and plays a role in multiple cellular processes including polarity and adhesion (1). PTK7 interacts with β-catenin and functions upstream from glycogen synthase kinase 3. PTK7 has been isolated from colon carcinoma and was designated colon carcinoma kinase-4 (2). In conjunction with other T cell markers, PTK7 has utility as a biomarker for detecting minimal residual disease of T-ALL in the bone marrow. PTK7 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cancer, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, and Neurobiology research.
序列
该【干冰】PTK7 recombinant protein-GST fusion protein - 009-001-T09的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】PTK7 recombinant protein-GST fusion protein - 009-001-T09的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】PTK7 recombinant protein-GST fusion protein - 009-001-T09的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.