PHLPP2 or PH domain and leucine rich repeat protein phosphatase 2 is the important regulators of Akt serine-threonine kinases and conventional/novel protein kinase C (PKC) isoforms. PHLPP1 and PHLPP2 differentially regulated AKT signaling by selectively dephosphorylating the hydrophobic motifs of AKT2 or AKT3. PHLPP may act as a tumor suppressor in several types of cancer due to its ability to block growth factor-induced signaling in cancer cells. PHLPP2 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, AKT/PKB Pathway, Cancer, Phosphatases, and PKA/PKC Pathway research.
序列
该【干冰】PHLPP2 recombinant protein-GST fusion protein - 009-001-S91的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】PHLPP2 recombinant protein-GST fusion protein - 009-001-S91的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】PHLPP2 recombinant protein-GST fusion protein - 009-001-S91的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
