【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90-【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein

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中文名称: 【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90

英文名字: 【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90

背景资料: PFTK1, also known as PFTAIRE protein kinase 1, is a member of the CDC2 -related protein kinase family which is expressed primarily in the postnatal and adult nervous system (1). PFTK1 is highly expressed in brain, pancreas, kidney, heart, testis, and ovary. PFTK1 interacts with 14-3-3-beta, 14-3-3-epsilon, 14-3-3-eta and 14-3-3-tau. Using PFTK1 mutant constructs and in vitro and in vivo binding studies, it was shown that PFTK1 amino acid residue ser119 is required for its interaction with all four 14-3-3 isoforms. (2). Significant upregulation of PFTK1 expression is observed in esophageal squamous cell carcinoma (ESCC). PFTK1 is not only useful as a prognostic marker in ESCC, but also as a predictor of the response to chemotherapy. PFTK1 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cancer, Cell Cycle, and Ser/Thr Kinases research.

序列: 该【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90的详细信息查看Rockland提供的产品说明书。

来源宿主: 该【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90的详细信息查看Rockland提供的产品说明书。

溶解建议: 该【干冰】PFTK1 (CDK14) recombinant protein-GST fusion protein - 009-001-S90的详细信息查看Rockland提供的产品说明书。

保存建议: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

其他: Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。