HO2, or heme oxygenase 2, belongs to the heme oxygenase family that are essential enzyme in heme catabolism that cleave heme to form biliverdin which is subsequently converted to bilirubin by biliverdin reductase (1). HO2 is part of the calcium-sensitive potassium channel complex and enhances channel activity in normoxia (2). Knockdown of HO2 expression reduces channel activity, an effect that is reversed by carbon monoxide. Inhibition of calcium-sensitive potassium channels by hypoxia is dependent on HO2 expression and is augmented by HO2 stimulation. HO2 Protein is ideal for investigators involved in Signaling Proteins, Cell Stress & Chaperone Proteins, Cardiovascular Disease, Cellular Stress, and Neurobiology research.
序列
该【干冰】HO2 recombinant protein-GST fusion protein - 009-001-S04S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】HO2 recombinant protein-GST fusion protein - 009-001-S04S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】HO2 recombinant protein-GST fusion protein - 009-001-S04S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
