FKBP1A is a member of the immunophilin protein family which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP1A is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and Rapamycin. FKBP1A interacts with various type I receptors, including the TGF-beta type I receptor and competitive binding assays show that the type I receptor may be a natural ligand for FKBP1A (1). FKBP1A-deficient mice have normal skeletal muscle but show severe dilated cardiomyopathy and ventricular septal defects that mimick a human congenital heart disorder (2). FKBP1A Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, AKT/PKB Pathway, Cardiovascular Disease, Inflammation, Neurobiology, and NfkB Pathway research.
序列
该【干冰】FKBP1A recombinant protein-GST fusion protein - 009-001-R94S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】FKBP1A recombinant protein-GST fusion protein - 009-001-R94S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】FKBP1A recombinant protein-GST fusion protein - 009-001-R94S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
