CyclinK is a member of the cyclin family which can regulate transcription through their association with and activation of cyclin-dependent kinases (CDK). The CDK/CyclinK complex can phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II (1). CyclinK is associated with potent CTD kinase and CDK kinase activities in vitro and coimmunoprecipitates with POLR2A. CyclinK is a new member of the transcription cyclin family which may play a dual role in regulating CDK and RNA polymerase II activities (2). Cyclin K Protein is ideal for investigators involved in Signaling Proteins, Cell Cycle Proteins, Cancer, and Cell Cycle research.
序列
该【干冰】CyclinK recombinant protein-GST fusion protein - 009-001-R81S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】CyclinK recombinant protein-GST fusion protein - 009-001-R81S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】CyclinK recombinant protein-GST fusion protein - 009-001-R81S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
