BIRC3 or baculoviral IAP repeat containing 3 is a member of the IAP family of proteins. BIRC3 inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and thereby interfering with activation of ICE-like proteases. BIRC3 inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. BIRC3 is a potential oncogene which is overexpressed in multiple lung cancers with or without higher copy numbers (1). BIRC3 is a key regulator of NOD innate immunity signaling (2). BIRC3 Protein is ideal for investigators involved in Signaling Proteins, Ubiquitin Proteins, Angiogenesis, Apoptosis/Autophagy, Cancer, Cell Cycle, and Inflammation research.
序列
该【干冰】BIRC3 recombinant protein-GST fusion protein - 009-001-R52S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】BIRC3 recombinant protein-GST fusion protein - 009-001-R52S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】BIRC3 recombinant protein-GST fusion protein - 009-001-R52S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
