- 中文名称
【干冰】14-3-3 sigma recombinant protein - 009-001-R32S
- 英文名字
- 【干冰】14-3-3 sigma recombinant protein - 009-001-R32S
- 供应商
- Rockland
- 产品货号
- 009-001-R32S
- 产品报价
- ￥询价/20ug
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- 14-3-3σ or stratifin is a protein that is strongly induced by gamma irradiation and other DNA-damaging agents (1). The induction of 14-3-3σ is mediated by a p53 responsive element. Exogenous introduction of 14-3-3σ into cycling cells results in a G2 cell cycle arrest (2). Knockout of 14-3-3σ in cells showed that the cells are unable to maintain cell cycle arrest after DNA damage. The 14-3-3σ -/- cells die as they enter mitosis. This process is associated with a failure of the 14-3-3σ-deficient cells to sequester the proteins that initiate mitosis and prevent them from entering the nucleus. Thus, 14-3-3σ plays an important role in maintaining the G2 checkpoint in cells and preventing mitotic death. 14-3-3σ Protein is ideal for investigators involved in Cell Stress& Chaperone Proteins, AKT/PKB Pathway, Cancer, Cell Cycle, Cellular Stress, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, and WNT Signaling research.
- 序列
- 该【干冰】14-3-3 sigma recombinant protein - 009-001-R32S的详细信息查看Rockland提供的产品说明书。
- 来源宿主
- 该【干冰】14-3-3 sigma recombinant protein - 009-001-R32S的详细信息查看Rockland提供的产品说明书。
- 溶解建议
- 该【干冰】14-3-3 sigma recombinant protein - 009-001-R32S的详细信息查看Rockland提供的产品说明书。
- 保存建议
- Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 其他
- Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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