CIP 1 (Cyclin-Dependent Kinase Inhibitor 1A) regulates cell cycle progression, terminal differentiation, and apoptosis (1). CIP1 was shown to be induced by p53 and to be a potent inhibitor of cyclin-dependent kinase (CDK) activity. DNA damage leads to increased expression of CIP1 in cyclin E-containing complexes and to an associated decrease in cyclin-dependent kinase activity. CIP1 is a critical downstream effector in the p53-specific pathway of growth control in mammalian cells (2). p21CIP1 Protein is ideal for investigators involved in Signaling Proteins, Cell Cycle Proteins, Cancer, and Cell Cycle research.
序列
该【干冰】p21CIP1 recombinant protein-GST fusion protein - 009-001-171的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】p21CIP1 recombinant protein-GST fusion protein - 009-001-171的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】p21CIP1 recombinant protein-GST fusion protein - 009-001-171的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
