CyclinD1 is a member of the cyclin family of proteins that are important regulators cyclin-dependent protein kinases (CDKs) (1). CyclinD1 forms a complex and functions as a regulatory subunit of CDK4 or CDK6 which are important during cell cycle G1/S transition. CyclinD1 has been shown to interact with the tumor suppressor protein Rb and the expression of CyclinD1 is positively regulated by Rb. Mutations, amplification and overexpression of CyclinD1 have been frequently observed in a variety of tumors and suggesting a role of this protein in tumorigenesis (2). CyclinD1 is ideal for investigators involved in Signaling Proteins, Cell Cycle Proteins, Cancer, and Cell Cycle research.
序列
该【干冰】CyclinD1 recombinant protein-GST fusion protein - 009-001-153S的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】CyclinD1 recombinant protein-GST fusion protein - 009-001-153S的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】CyclinD1 recombinant protein-GST fusion protein - 009-001-153S的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
