Labelled S-(5’-Adenosyl)-L-methionine. Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.Melting Point: >110°C (dec.) (decomposes)Solubility: Water (Slightly)Method for Determining Identity:Proton NMR spectroscopic analysis (D2O) and Mass spectrometric analysisTLC Conditions: C18; Methanol: Water : Acetic Acid (5:5:1). Visualized with UV, Ninhydrin and KMnO4 (Rf=0.45).Elemental Analysis:Calculated: %C: 30.15, %H: 4.39, %N: 14.06Normalized Intensity:As reportedSulfate Content: ~33%Water Content:~3%Ethanol: ~3%Storage and Stability:Store at -20°C under an atmosphere of inert gas. Stable for 6 months after receipt. Caution: Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
产品形式
该产品为白色或淡黄色固体。
保存建议
接收到S-(5'-Adenosyl)-L-Methionine-d3 Disulfate Salt (Mixture of Diastereomers)产品后,置于-20°C温度下保存。