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中文名称

重组 抗-小鼠 PD-1 小鼠 IgG1 Kappa 单克隆抗体 (Clone 29F.1A12.1)

英文名字
Recombinant Anti-mouse PD-1 Mouse IgG1 Kappa Monoclonal Antibody (Clone 29F.1A12.1)
供应商
Promab
产品货号
PMB-B00071.m1
产品报价
¥询价/5mg
产品说明书
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产品新闻
背景资料
The rat anti-mouse PD-1 monoclonal antibody 29F.1A12 (rat IgG2a kappa) reacts with the mouse PD-1 protein (programmed death-1 or CD279) encoded by the mouse Pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD-1 and anti-mouse PD-L1 antibodies which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The 29F.1A12 monoclonal antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein.nnOur recombinant 29F.1A12 antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse PD-1 monoclonal antibody (hybridoma clone name or number: 29F.1A12).
应用类型
ELISA, WB, Flow cytometry, IHC, ICC, animal model study
免疫原
The original rat hybridoma (clone name: 29F.1A12) was generated by immunizing rats with the mouse PD-1 cDNA followed by the mouse PD-1-Ig fusion protein.
来源宿主
CHO cells
反应性
Mouse
保存建议
Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
其他
programmed cell death protein 1, PD-1, CD279, cluster of differentiation 279, 29F.1A12
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