- 中文名称
重组 抗-小鼠 PD-1 小鼠 IgG1 Kappa 单克隆抗体 (Clone RMP1-14.1)
- 英文名字
- Recombinant Anti-mouse PD-1 Mouse IgG1 Kappa Monoclonal Antibody (Clone RMP1-14.1)
- 供应商
- Promab
- 产品货号
- PMB-B00070.m1
- 产品报价
- ￥询价/5mg
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- The rat anti-mouse PD-1 monoclonal antibody (clone No. RMP1-14, rat IgG2a kappa) reacts with the mouse PD-1 protein (CD279 or programmed death-1) encoded by the mouse pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD 1 antibody and the anti-mouse PD L1 antibody which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The RMP1-14 antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein.nnOur recombinant RMP1-14 antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse PD-1 antibody (hybridoma clone name or number: RMP1-14). The murinized anti-mouse PD-1 recombinant antibody has not only the constant regions of the mouse IgG antibodies but also the murinized variable regions.
- 应用类型
- ELISA, WB, Flow cytometry, IHC, ICC, animal model study
- 免疫原
- The original rat hybridoma (clone name: RMP1-14) was generated by immunizing Sprague Dawley rats with mouse PD-1-transfected BHK cells and using a P3U1 myeloma as the fusion partner.
- 来源宿主
- CHO cells
- 反应性
- Mouse
- 保存建议
- Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
- 其他
- Programmed Cell Death Protein 1, PD-1, CD279, Cluster of Differentiation 279, RMP1-14
- 注意
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