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中文名称

Ep大鼠uzumab 生物类似药, 内毒素 0.05 EU/mg

英文名字
Epratuzumab Biosimilar, Endotoxin 0.05 EU/mg
供应商
Promab
产品货号
PMB-B00039.05
产品报价
¥询价/5mg/20mg
产品说明书
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产品新闻
背景资料
Epratuzumab Biosimilar uses the same protein sequences as the therapeutic antibody epratuzumab.nnEpratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.nnEpratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).
应用类型
Flow cytometry, animal model study
免疫原
Human CD22
来源宿主
CHO cells
反应性
Human
保存建议
Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
其他
cluster of differentiation-22, SIGLEC-2, SIGLEC2
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