Pancreatitis-associated protein （PAP） is a secretory protein not normally expressed in healthy pancreas but highly induced during acute pancreatitis. While PAP has been shown to be anti-bacterial and antiapoptotic in vitro， its definitive biological function in vivo is not clear. Using antisepse oligonucleotides， inhibition of PAP expression significantly worsened pancreatitis in a rat model. During pancreatitis， PAP released by the pancreas could mediate lung inflammation through induction of hepatic TNF- alpha expression and subsequent increase in circulating TNF-alpha.
应用类型
【PAP-1】兔抗人再生胰岛衍生蛋白3aPolyclonal Rabbit Anti Human Pancreatitis-associated protein 该产品的应用类型查阅产品说明书。
免疫原
Immunoaffinity chromatography on a column with immobilized recombinant human REG3A.
来源宿主
提供的【PAP-1】兔抗人再生胰岛衍生蛋白3aPolyclonal Rabbit Anti Human Pancreatitis-associated protein 产品，该来源宿主查看产品说明书。
