PTPRM is a member of the protein tyrosine phosphatase family and can participate in a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation (1). PTPRM has been shown to mediate cell-cell aggregation through the interaction with another molecule of PTPRM on an adjacent cell. PTPRM can interact with scaffolding protein RACK1/GNB2L1 and this interaction may be necessary for downstream signaling in response to cell-cell adhesion (2). PTPRM has been shown to be expressed in human pulmonary vascular endothelia where it directly binds to VE-cadherin and regulates both the tyrosine phosphorylation state of VE-cadherin and barrier integrity. PTPRM Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cardiovascular Disease, Neurobiology, and Phosphatases research.
序列
该【干冰】PTPRM (PTP-m) recombinant protein-GST fusion protein - 009-001-T11的详细信息查看Rockland提供的产品说明书。
来源宿主
该【干冰】PTPRM (PTP-m) recombinant protein-GST fusion protein - 009-001-T11的详细信息查看Rockland提供的产品说明书。
溶解建议
该【干冰】PTPRM (PTP-m) recombinant protein-GST fusion protein - 009-001-T11的详细信息查看Rockland提供的产品说明书。
保存建议
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
