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Relia Tech:抗原亲和纯化LYVE1抗体

发布者:艾美捷科技    发布时间:2022-07-28     


LYVE-1(Lymphatic Vessel Endothelial Receptor-1),淋巴管内皮受体1 是白细胞受体CD44的近亲,LYVE-1的推断氨基酸序列显示,它是一个具有322个残基的I型整体膜多肽,与CD44的HA受体有41%的相似性,其胞外结构域为212个残基,包含一个Link模块,即Link蛋白超家族的原型HA结合域。与CD44一样,LYVE-1分子同时结合可溶性和固定化的HA。然而,与CD44不同的是,LYVE-1分子在淋巴管壁的管腔面上与HA共定位,而在血管中则完全没有。LYVE1是淋巴管内皮细胞透明质酸(HA)的主要受体,是区分血管和淋巴管的常用标志物。  


  一般的抗体生产公司通常会使用Protein A/G进行亲和纯化抗体,这样生产的抗体亲和力和纯度很难达到理想的高度。作为专业的生命科学医药原料和解决方案供应商,艾美捷科技为您推荐德国,Relia Tech荣誉出品:抗原亲和纯化的,LYVE1抗体,Nature, Cell都在用! 


产品名称Rabbit Anti-Human Lyve-1Rabbit Anti-Mouse Lyve-1
特异性人 (不与Mouse交叉反应)
应用类型WB, IHC (P, F), IF,FCWB, IHC (C), IF, FC
产品形式50ug冻干粉(仅含PBS盐);建议加无菌水重溶至0.1 - 1 mg/ml.
保存条件冻干粉抗体在 -20℃保存 2 年。无菌复溶后,抗体可在 2-8℃下稳定长达 6 个月。冷冻等分试样在 -20℃下可稳定保存至少 6个月。对于冷冻等分试样,建议添加载体蛋白或 50% 甘油。

* 以上产品仅限科研使用,不得用于人体或医疗。 



来自《Nature》Rantakari, Pia et al. "Fetal liver endothelium regulates the seeding of tissue-resident macrophages". Nature vol. 538,7625 (2016): 392-396.  



来自《Cell》 Okabe, Keisuke, et al. "Neurons limit angiogenesis by titrating VEGF in retina." Cell 159.3 (2014): 584-596.   


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