英文名字 LC3B polyclonal antibody
中文名称 LC3B 多克隆抗体
供应商 Viva Bioscience
产品货号 VB2930-50
产品报价 ¥3750/50ug
购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868
产品新闻
背景资料 Formation and expansion of the pre-autophagosomal structure in yeast requires the attachment of the ubiquitin-like protein Atg8 via its C-terminal glycine to the amino group of phosphatidylethanolamine (PE), enabling its anchoring to the isolation membrane of the autophagosome. In mammals, Atg8 is represented by at least six orthologs that fall into two subgroups, LC3- and GABARAP-like proteins and the free and PE linked versions of these proteins are often referred to as LC3-I and LC3-II respectively.

Whilst the specific roles for each individual protein have yet to be fully elucidated they have been shown to be involved in binding and selection of ubiqitinated autophagy substrate proteins, via ubiquitin / LC3 binding receptor proteins such as p62, in addition to their role in autophagosome biogenesis. Release of LC3 / GABARAP proteins via their cleavage from the mature autophagosome structure by Atg4 proteases facilitates their recycling and may be a requirement for autophagosome-lysosome fusion to take place.
应用类型 该LC3B 多克隆抗体经过WB等实验验证。推荐使用稀释比率分别为:WB 1:500-1000。
免疫原 Peptide derived from N-terminal region of human LC3B protein
来源宿主
反应性 人,小鼠,大鼠
保存建议 建议在收到LC3B 多克隆抗体产品后可将其置于4度稳定保存1个月。-20度稳定保存1年,避免反复冻融,建议分装保存!
产品说明书
其他 英国Viva Bioscience公司是一家研发、生产并销售蛋白降解相关产品的公司。其产品主要用于细胞自噬、泛素化和蛋白酶体研究(也覆盖其他蛋白降解相关的产品),其产品价格合理、质量可靠且具有创新性。目前VIVA Bioscience提供逾460种产品,涉及细胞自噬、蛋白泛素化和讲解相关的所有试剂盒、蛋白、底物以及多种抑制剂、激活剂等全系列产品。作为多家进口品牌的中国区域总代理,艾美捷科技与Viva Bioscience一道为中国科研工作者们提供更好、更新的自噬、泛素化和蛋白酶体等研究工具。

相关产品

首页 公司简介 新闻中心 产品中心 特色产品 技术专栏 在线订购 联系我们

版权所有 艾美捷科技有限公司

地址:武汉市洪山区光谷大道35号光谷总部国际二期时代1栋13楼 邮政编码:430074

电话:+86-027-59626688 全国免费技术支持: 400-6800-868 传真:+86-027-59716800

鄂ICP备10204150号

Abbkine Scientific   亚科因科技