ZnT3 is a member of the SLC30 family of zinc transporters which promotes the influx of zinc ions into synaptic vesicles of glutamatergic neurons from the cytoplasm, intracellular organelles, or to the outside of the cell. It is responsible for maintaining high intravesicular zinc content.nZnT3 is encoded by the Slc30a3 gene and is selectively located on the vesicles of zinc-secreting neurons. ZnT3 is also present in regions of the brain such as the hippocampus and neocortex1. Ionic zinc is found ubiquitously throughout synapses of the mammalian central nervous system, where it plays fundamental roles in synaptic function and plasticity
