- 中文名称
甘氨酸受体Alpha1抗体（50 ul）
- 英文名字
- Anti-Glycine Receptor Alpha1
- 供应商
- Alomone
- 产品货号
- ALO-AGR-001-50
- 产品报价
- ￥已停产
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868。
- 产品新闻
- 背景资料
- Glycine receptors (GlyRs) mediate ionotropic inhibitory neurotransmission in the CNS where they play an essential role in inhibition of motor neurons in the spinal cord and brainstem1. The glycine receptor is composed of three ligand-binding subunits of 48 kDa (α) and two homologous polypeptides of 58 kDa (β) that span the postsynaptic membrane in a pentameric arrangement to form a Cl--selective channel2. So far, at least three different α-subunit variants of the GlyR have been identified: α1, α2 and α33. Homo-oligomeric α2 receptors have a low strychnine-binding affinity and are considered to represent a neonatal form of GlyR, which is replaced during development by receptors containing the α1 subunit. Adult GlyRs are predominantly composed of α1 and β subunits, the α3 subunit being expressed at low levels in only a few brain regions.nGlyRα1 subunits are widely expressed and contribute to many processes in the CNS, including inflammatory pain perception, modulation of auditory and visual pathways, and neurotransmission in the cerebellar cortex.Mutations in glycine receptor α1 subunits cause human hereditary hyperekplexia, a disorder characterized by an exaggerated startle response, which is a consequence of the role of GlyRs in motor reflex circuits of the spinal cord.
- 应用类型
- 经验证，该抗体可应用于IH、WB等实验应用，也可用于IC、IFC、IP等实验。
- 免疫原
- Glycine 受体 Alpha1抗体的免疫原肽段为(C)RHHKSPMLNLFQD。此免疫原序列来源于350-362 位氨基酸残基，该序列来源于大鼠GlyRα1(Accession编号为P07727)。 第二胞内环。
- 来源宿主
- 兔
- 反应性
- 反应性：小鼠、 大鼠、也可反应于： 人
- 保存建议
- 艾美捷为您提供的Glycine 受体 Alpha1抗体(50 ul)为室温运输，建议您收到产品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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