中文名称

【VEGFR2】人源细胞表达的重组人血管内皮生长因子受体2 / Flk-1 / KDR（100 ug）

英文名字

Human CellExp VEGFR2/Flk-1/KDR, human recombinant

供应商

Biovision

产品货号

7399-100

产品报价

￥已停产

产品说明书

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产品新闻

背景资料

Kinase insert domain receptor (KDR) also known as CD309, FLK1, VEGFR, VEGFR2, and is one of the subtypes of VEGFR. VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. The VEGF receptors have an extracellular portion consisting of 7 immunoglobulin-like domains, a single transmembrane spanning region and an intracellular portion containing a split tyrosine-kinase domain. VEGF-A binds to VEGFR-1 (Flt-1) and VEGFR-2 (KDR/Flk-1). VEGFR-2 appears to mediate almost all of the known cellular responses to VEGF. The function of VEGFR-1 is less well defined, although it is thought to modulate VEGFR-2 signaling. Another function of VEGFR-1 may be to act as a dummy/decoy receptor, sequestering VEGF from VEGFR-2 binding (this appears to be particularly important during vasculogenesis in the embryo). In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions.

序列

人源细胞表达的重组人血管内皮生长因子受体2/Flk-1/KDR蛋白产品，又称KDR, CD309, FLK1, VEGFR, VEGFR2, kinase insert domain receptor.其对应NCBI基因号为3791，对应Accession号为P35968.

来源宿主

提供的【VEGFR2】人源细胞表达的重组人血管内皮生长因子受体2/Flk-1/KDR产品的来源为人胚肾HEK293细胞重组表达重组表达.

溶解建议

人源细胞表达的重组人血管内皮生长因子受体2/Flk-1/KDR产品请按照说明书建议进行溶解操作：Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

保存建议

在您收到艾美捷发出的【VEGFR2】人源细胞表达的重组人血管内皮生长因子受体2/Flk-1/KDR产品后，建议将其置于-20°C保存.

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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