Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells.{8458} Progesterone activates the human progesterone receptor with an EC50 value of 0.5 nM.{25839}
产品描述
The biosynthetic precursor of all other steroid hormones; activates the human progesterone receptor with an EC50 value of 0.5 nM
