NPHP4 encodes a protein involved in renal tubular development and function. Nephrocystin-4 interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants. 蛋白别名为:NPHP4; KIAA0673; Nephrocystin-4; Nephroretinin;基因ID为:261734;蛋白质ID:O75161
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Nephrocystin-4. at AA rangle: 850-930