Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-11 is also synthesized as inactive pro-enzyme that are processed in cells undergoing apoptosis or inflammation. The processed form of caspase-11 consists of large and small subunits which associate to form an active enzyme.
应用类型
Western blotting （0.5-4 ug/ml）. The antibody detects procaspase-11 （45 kDa）， a partially cleaved fragment （30 kDa） and fully cleaved fragment （20 kDa）. A 58 kDa unknown identity band was also detected in 3T3 cells.
免疫原
Synthetic peptide surrounding amino acid 257 of rat caspase-11
来源宿主
兔
反应性
经检测验证，可与小鼠、大鼠种属来源的Caspase-11蛋白发生免疫反应.
保存建议
提供的Caspase-11抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Caspase-11抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
